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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Francisco Burgos | 0.853 | 2028 | |
| 2 | David Rubin# | 1.000 | 2053 | |
| 3 | Marlon Harris | 1.072 | 2044 | |
| 4 | Armando Ortíz | 1.177 | 2025 | |
| 5 | Paul Addison | 1.186 | 2026 | |
| 6 | Li-zhi Lai | 1.249 | 2050 | |
| 7 | Tomás Vargas | 1.280 | 2026 | |
| 8 | Benjamin Busto | 1.319 | 2027 | |
| 9 | Bob O'Slattery | 1.324 | 2051 | |
| 10 | Donald Scott | 1.337 | 2050 | |
| 11 | Colton Phillips | 1.344 | 2053 | |
| 12 | Sylvain Richard | 1.350 | 2040 | |
| 13 | William Averett | 1.354 | 2043 | |
| 14 | Ismael Soto | 1.355 | 2021 | |
| 15 | Tony Solíz | 1.376 | 2024 | |
| 16 | Ronald Johnson | 1.395 | 2050 | |
| 17 | Jonah Cervantes# | 1.429 | 2058 | |
| 18 | Steven Weaver# | 1.430 | 2056 | |
| 19 | Edison Carter | 1.435 | 2037 | |
| 20 | Dave Hanna# | 1.436 | 2060 | |
| 21 | Bob Browning | 1.450 | 2025 | |
| 22 | Akil bin Abbud# | 1.491 | 2057 | |
| 23 | Edward Martin | 1.563 | 2042 | |
| 24 | José Cotilla | 1.577 | 2029 | |
| 25 | Kevin Coleville# | 1.593 | 2060 | |
| 26 | Baruc Garibay | 1.627 | 2027 | |
| 27 | Jesús Sánchez | 1.641 | 2053 | |
| 27 | Loren Berdine | 1.641 | 2029 | |
| 29 | Elijah Cox | 1.646 | 2052 | |
| 29 | Ron Harris# | 1.646 | 2058 | |
| 31 | Iván Vázquez | 1.662 | 2027 | |
| 32 | Vitale Piantini# | 1.706 | 2057 | |
| 33 | Ronald Love | 1.712 | 2045 | |
| 34 | Tony Smith# | 1.725 | 2062 | |
| 35 | Felipe Lozano | 1.748 | 2028 | |
| 36 | Mark Cunningham# | 1.757 | 2054 | |
| 37 | Fernando Feliciano# | 1.768 | 2061 | |
| 38 | Min-chin Kim | 1.779 | 2029 | |
| 39 | Michael Phillips# | 1.809 | 2058 | |
| 40 | Brian Campbell | 1.810 | 2047 | |
| 41 | José López# | 1.811 | 2057 | |
| 42 | Steve Romero# | 1.823 | 2057 | |
| 43 | Greg Hoover | 1.824 | 2038 | |
| 44 | Don Bender | 1.831 | 2020 | |
| 45 | Jorge Travieso | 1.832 | 2028 | |
| 46 | Robbie Edmond | 1.865 | 2053 | |
| 47 | Ángel Franco | 1.874 | 2043 | |
| 48 | Alberto Solís | 1.885 | 2027 | |
| 49 | Yoshitaka Shinohara# | 1.886 | 2056 | |
| 50 | Daisuke Yoshikawa | 1.893 | 2047 | |
| 51 | Ed Moore | 1.911 | 2053 | |
| 52 | Júlio Vázquez | 1.912 | 2026 | |
| 53 | Gary Smith | 1.923 | 2050 | |
| 54 | Steve Young | 1.924 | 2040 | |
| 55 | Wilbert Irwin# | 1.929 | 2055 | |
| 55 | Kenzaburo Hakui | 1.929 | 2037 | |
| 55 | Wendell Latham# | 1.929 | 2060 | |
| 58 | Enrique Castro | 1.933 | 2027 | |
| 59 | Ashley Remington | 1.941 | 2053 | |
| 60 | Kong Li | 1.948 | 2035 | |
| 61 | Santiago Alonza | 1.958 | 2023 | |
| 62 | Will Hoffman | 1.964 | 2029 | |
| 63 | Jang-jin Na# | 1.967 | 2060 | |
| 64 | Bhagavan Antle | 1.972 | 2041 | |
| 65 | Jordon Glen Anderson | 1.973 | 2040 | |
| 66 | José Durán# | 1.976 | 2054 | |
| 67 | Hsin-ta Lian | 1.978 | 2041 | |
| 67 | Tony Moreno | 1.978 | 2028 | |
| 69 | Todd Lee# | 1.983 | 2057 | |
| 70 | Bobby Roode | 1.987 | 2030 | |
| 71 | Francisco Encarnación# | 1.991 | 2050 | |
| 72 | Jesús Bojórquez# | 2.000 | 2060 | |
| 73 | Robby MacGregor | 2.006 | 2054 | |
| 74 | Wijnand Boone | 2.007 | 2056 | |
| 75 | Ed Hull# | 2.011 | 2061 | |
| 76 | Luis Hernández | 2.017 | 2025 | |
| 77 | Todd O'Looney | 2.029 | 2053 | |
| 78 | Maru Pao Pao | 2.030 | 2027 | |
| 78 | Francisco Burgos | 2.030 | 2027 | |
| 78 | Juan López | 2.030 | 2021 | |
| 81 | Steve Stevens | 2.044 | 2053 | |
| 82 | Tyler Lund | 2.048 | 2026 | |
| 83 | Jesús Sánchez | 2.050 | 2054 | |
| 84 | Fernando Fonseca# | 2.053 | 2053 | |
| 84 | Ron Madison | 2.053 | 2020 | |
| 86 | Sam Martínez | 2.055 | 2042 | |
| 86 | Ernesto Méndez | 2.055 | 2034 | |
| 86 | Javier Ariza | 2.055 | 2036 | |
| 89 | Rusty Swanson | 2.056 | 2025 | |
| 90 | Ramón Castaneda | 2.057 | 2025 | |
| 91 | Mathias Monnier# | 2.061 | 2058 | |
| 92 | Claudio Mateo | 2.064 | 2029 | |
| 93 | Rafael Videla | 2.082 | 2056 | |
| 94 | Bob O'Slattery | 2.083 | 2052 | |
| 95 | Darius Baxa | 2.098 | 2026 | |
| 96 | Gabriel Escobar | 2.101 | 2025 | |
| 97 | Osiris St. Brown | 2.103 | 2028 | |
| 98 | Ed Moore | 2.109 | 2052 | |
| 99 | Sean Halls | 2.111 | 2036 | |
| 100 | Steve Baker | 2.112 | 2042 |
