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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Manuel Villarreal | 215 | 2013-2022 | |
| 2 | Jorge Herrera | 199 | 2035-2052 | |
| 3 | Mariano Juderías# | 174 | 2042-2054 | |
| 4 | Wilbur Davis | 160 | 2026-2041 | |
| 5 | Karl Schultz | 102 | 2020-2032 | |
| 6 | Pedro Willis | 92 | 2013-2024 | |
| 7 | Rafael Martínez | 87 | 2043-2049 | |
| 8 | Jur Prokop | 85 | 2036-2048 | |
| 9 | Neil Lawson | 83 | 2016-2031 | |
| 10 | Pancho García | 78 | 2013-2025 | |
| 11 | Michael Malloy | 76 | 2027-2042 | |
| 12 | Daniel McCoy | 70 | 2032-2049 | |
| 12 | John Yossarian# | 70 | 2042-2053 | |
| 14 | Melvin Castro* | 65 | 2020-2035 | |
| 15 | Terrence Eler | 63 | 2018-2033 | |
| 16 | Stanley Belote | 61 | 2027-2037 | |
| 16 | Bernardo Elías | 61 | 2019-2032 | |
| 16 | Yong-hong Ren# | 61 | 2043-2054 | |
| 19 | Alfredo Martínez* | 56 | 2025-2041 | |
| 20 | James Murray | 54 | 2013-2022 | |
| 21 | Glyn Bolasky | 52 | 2029-2044 | |
| 21 | Rob Brooks | 52 | 2036-2046 | |
| 23 | Sasha Mamchenko# | 51 | 2050-2054 | |
| 23 | Fernando Soto | 51 | 2038-2045 | |
| 25 | Armando Esparza | 50 | 2015-2027 | |
| 25 | Ishaan Swan# | 50 | 2047-2053 | |
| 25 | Craig Woods | 50 | 2037-2049 | |
| 28 | Chris Payling | 49 | 2028-2045 | |
| 29 | Jerry Harris | 46 | 2013-2019 | |
| 30 | Robert Adams | 45 | 2023-2029 | |
| 30 | Miguel Chávez | 45 | 2017-2021 | |
| 30 | Jasper Morrison | 45 | 2034-2043 | |
| 30 | Ramón Souza | 45 | 2018-2029 | |
| 30 | Marcos Zúñiga | 45 | 2014-2020 | |
| 35 | Jesús Vargas | 44 | 2029-2045 | |
| 36 | Francisco De La Cruz# | 41 | 2047-2054 | |
| 37 | Arturo Hernández | 39 | 2013-2019 | |
| 38 | Pedro Castillo | 37 | 2028-2032 | |
| 38 | Mike Gardner | 37 | 2018-2032 | |
| 38 | Tae-cho Han | 37 | 2031-2044 | |
| 41 | Rafael Arredondo | 36 | 2024-2032 | |
| 41 | Quincy Wass | 36 | 2042-2053 | |
| 41 | Arthur Witter# | 36 | 2046-2052 | |
| 44 | Tim Hargrove | 35 | 2016-2027 | |
| 44 | Eisse van Opdorp# | 35 | 2038-2053 | |
| 46 | Harry Cornelis | 34 | 2040-2046 | |
| 46 | Tom Smythe# | 34 | 2037-2054 | |
| 48 | Manuel Carmona | 32 | 2025-2042 | |
| 48 | Don Clark# | 32 | 2046-2052 | |
| 48 | Omar Luoa# | 32 | 2043-2051 | |
| 51 | Daniel Marley# | 31 | 2044-2053 | |
| 51 | Enrique Marroquín | 31 | 2020-2032 | |
| 53 | Esteban Sifuentes# | 30 | 2042-2050 | |
| 54 | Wilfred McLaughlin* | 29 | 2018-2033 | |
| 54 | José Ruíz | 29 | 2027-2038 | |
| 54 | Mal Wadley | 29 | 2015-2028 | |
| 57 | León Castillo# | 28 | 2039-2050 | |
| 57 | Félix Pérez | 28 | 2013-2022 | |
| 57 | Guillermo Romero | 28 | 2013-2021 | |
| 60 | Julián Flores# | 27 | 2049-2052 | |
| 60 | Gilberto Ocasio | 27 | 2036-2045 | |
| 60 | Dhataki Pummy# | 27 | 2046-2053 | |
| 60 | Pedro Vázquez | 27 | 2023-2036 | |
| 64 | Iiri Haapajarvi | 26 | 2039-2047 | |
| 64 | Jérôme Masson | 26 | 2029-2038 | |
| 64 | Ken Norman | 26 | 2015-2022 | |
| 64 | Michael Witt | 26 | 2037-2043 | |
| 68 | Joey Jones | 25 | 2019-2031 | |
| 68 | Rick Mayfield | 25 | 2028-2036 | |
| 68 | Jon Osterman | 25 | 2028-2044 | |
| 71 | Yuk Cuan# | 23 | 2050-2054 | |
| 71 | Gustavo Gonzáles# | 23 | 2045-2053 | |
| 71 | Raúl Robles | 23 | 2017-2025 | |
| 71 | Yoichibei Sato | 23 | 2026-2033 | |
| 71 | Iván Vega | 23 | 2023-2037 | |
| 76 | David Breitling | 22 | 2028-2031 | |
| 76 | Brad Elmore | 22 | 2015-2025 | |
| 76 | David Hubbard | 22 | 2020-2026 | |
| 76 | Ramón Rodríguez | 22 | 2032-2043 | |
| 80 | Vicente Gomillion | 21 | 2040-2045 | |
| 80 | Zahid Kashani | 21 | 2030-2043 | |
| 80 | Sherman Kline | 21 | 2042-2046 | |
| 80 | Arsenio Laurel | 21 | 2030-2040 | |
| 80 | Carl Nash | 21 | 2013-2014 | |
| 85 | Guillermo Dettori# | 20 | 2044-2054 | |
| 85 | Tommy Jones* | 20 | 2015-2036 | |
| 85 | Nick Leonard | 20 | 2017-2021 | |
| 85 | Nick Simmons | 20 | 2014-2022 | |
| 85 | Rafael Sánchez | 20 | 2025-2035 | |
| 90 | Kelvin Abbott | 19 | 2032-2037 | |
| 90 | Sherman Davis | 19 | 2013-2022 | |
| 90 | Freek Derksen# | 19 | 2050-2053 | |
| 90 | Gabriel Montoya | 19 | 2037-2041 | |
| 90 | Miguel Morán | 19 | 2026-2032 | |
| 90 | Luis Rivas | 19 | 2015-2024 | |
| 90 | Daniel Ruíz | 19 | 2013-2017 | |
| 97 | Ye Der | 18 | 2018-2028 | |
| 97 | Shohei Kiyomizu | 18 | 2025-2034 | |
| 99 | Qutuz bin Nazeeh# | 17 | 2049-2054 | |
| 99 | Bill Burgess | 17 | 2015-2025 |
