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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Min Der# | 1.628 | 2051 | |
| 2 | Jesús Sánchez | 1.655 | 2056 | |
| 3 | Steven Weaver# | 1.696 | 2057 | |
| 4 | John Bell# | 1.699 | 2059 | |
| 5 | Jesús Hernández | 1.713 | 2027 | |
| 6 | Jorge Enríquez | 1.761 | 2050 | |
| 7 | Emílio Mavarro | 1.833 | 2028 | |
| 8 | Yaichiro Shini | 1.868 | 2046 | |
| 9 | Norberto Concepción | 1.950 | 2030 | |
| 10 | Warren Evans# | 2.042 | 2058 | |
| 11 | Homer Sanders | 2.124 | 2048 | |
| 12 | César Pinto | 2.125 | 2050 | |
| 13 | Edward Lamb | 2.130 | 2058 | |
| 14 | Marnix van Rijn | 2.146 | 2032 | |
| 15 | Alberto Nieves# | 2.152 | 2050 | |
| 16 | Brian Hill# | 2.184 | 2053 | |
| 17 | Kris Collins | 2.201 | 2053 | |
| 17 | Gaberiela Tatafu | 2.201 | 2042 | |
| 19 | Martín Orozco# | 2.219 | 2062 | |
| 20 | José Zamora | 2.229 | 2050 | |
| 21 | Brian Walker | 2.238 | 2028 | |
| 22 | Wayland Whitlock | 2.250 | 2041 | |
| 23 | Curt Tate | 2.301 | 2024 | |
| 24 | Manuel Juárez# | 2.317 | 2060 | |
| 25 | Forest Bell | 2.319 | 2040 | |
| 25 | Anthony Patterson# | 2.319 | 2052 | |
| 27 | David Meyer# | 2.326 | 2058 | |
| 28 | John Boyle | 2.334 | 2024 | |
| 29 | Luis Ortíz | 2.338 | 2025 | |
| 30 | Jeff Morehead | 2.345 | 2048 | |
| 31 | Javier Merlo | 2.362 | 2043 | |
| 32 | Henry Tucker# | 2.365 | 2052 | |
| 33 | Norberto Concepción | 2.390 | 2029 | |
| 34 | Ryan Glover# | 2.400 | 2062 | |
| 35 | Akil bin Abbud# | 2.408 | 2058 | |
| 36 | Barney Starr | 2.412 | 2028 | |
| 37 | Sumiteru Uemura# | 2.414 | 2062 | |
| 38 | Santo Velazco | 2.418 | 2028 | |
| 39 | Bhunandana Lecamwasam | 2.423 | 2050 | |
| 40 | John Ball | 2.438 | 2027 | |
| 41 | Daniel Riley | 2.439 | 2027 | |
| 42 | Jesús Cruz | 2.440 | 2037 | |
| 43 | Randy Crane | 2.441 | 2053 | |
| 44 | Kenny Riley# | 2.448 | 2058 | |
| 45 | Carlos Pérez | 2.455 | 2022 | |
| 46 | William Edwards# | 2.469 | 2060 | |
| 47 | Doug Morgan# | 2.476 | 2058 | |
| 48 | Trevor Covenay | 2.477 | 2058 | |
| 49 | Niek Proeme# | 2.495 | 2061 | |
| 50 | Edwin Rice | 2.497 | 2057 | |
| 51 | Alan Gilbert | 2.505 | 2052 | |
| 52 | Elvin Olson# | 2.513 | 2052 | |
| 53 | Lance Farmer | 2.527 | 2041 | |
| 54 | Rick Hartsfield# | 2.536 | 2060 | |
| 55 | Montrell Baxa | 2.537 | 2032 | |
| 56 | Jeff McClorey | 2.548 | 2059 | |
| 57 | Brent Richardson | 2.556 | 2053 | |
| 58 | Johnnie Bough | 2.557 | 2032 | |
| 59 | Jack Peters# | 2.563 | 2053 | |
| 59 | Tony DeWitt | 2.563 | 2030 | |
| 61 | Jesús Sánchez | 2.564 | 2057 | |
| 62 | Rob Silva | 2.569 | 2026 | |
| 63 | Lawrence Swift | 2.577 | 2035 | |
| 64 | Kelvin van Enk# | 2.579 | 2051 | |
| 65 | Shotaro Sugahara | 2.581 | 2028 | |
| 66 | Milutin Panic | 2.591 | 2040 | |
| 67 | Daniel Lavalley | 2.593 | 2032 | |
| 68 | Osvaldo Garibe | 2.598 | 2029 | |
| 69 | David Uribe# | 2.602 | 2058 | |
| 70 | Bobby Monroe# | 2.603 | 2061 | |
| 71 | Michael Carlson# | 2.611 | 2061 | |
| 72 | Lance Mascola | 2.615 | 2043 | |
| 72 | Mason Hatcher | 2.615 | 2057 | |
| 74 | Vincente Ramos# | 2.618 | 2061 | |
| 75 | Ted Elkins# | 2.626 | 2057 | |
| 76 | Miguel Aguilar | 2.627 | 2025 | |
| 77 | Paco Manuel | 2.646 | 2028 | |
| 78 | David Guerra# | 2.650 | 2052 | |
| 79 | Mark Walker | 2.653 | 2023 | |
| 80 | Norberto Quintana | 2.657 | 2024 | |
| 81 | Aaron Ellicott | 2.661 | 2057 | |
| 82 | Dan Bond | 2.663 | 2039 | |
| 83 | Loeck Visser | 2.667 | 2026 | |
| 84 | Doyle Manning# | 2.684 | 2061 | |
| 85 | Kane Hallworth | 2.700 | 2049 | |
| 85 | Héctor Peña | 2.700 | 2055 | |
| 85 | Pedro Reynoso | 2.700 | 2030 | |
| 88 | José Peña# | 2.715 | 2056 | |
| 89 | Eddy Boyd | 2.716 | 2046 | |
| 90 | Manuel Delgado | 2.718 | 2021 | |
| 91 | Dan Hewitt# | 2.719 | 2059 | |
| 92 | Travis Grant | 2.730 | 2023 | |
| 92 | Jorge Carrión | 2.730 | 2025 | |
| 94 | Wilson Alindogan | 2.732 | 2040 | |
| 95 | Ánibal Ramos# | 2.749 | 2058 | |
| 96 | Chris Small | 2.752 | 2051 | |
| 97 | Rick Dunlap | 2.759 | 2053 | |
| 98 | Davey de Haan | 2.760 | 2057 | |
| 99 | Eduardo Soto# | 2.765 | 2057 | |
| 100 | Pascal Martin | 2.769 | 2037 |
