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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Robin Cecchini# | 0.748 | 2060 | |
| 2 | Chad May# | 1.036 | 2060 | |
| 3 | Neil Smith# | 1.213 | 2059 | |
| 4 | Davey de Haan | 1.312 | 2054 | |
| 5 | Chris Johnston# | 1.387 | 2057 | |
| 6 | Bubba Orr# | 1.398 | 2059 | |
| 7 | Manny Rodríguez | 1.400 | 2039 | |
| 8 | Jorge Flores# | 1.496 | 2060 | |
| 9 | Félix Aiza | 1.504 | 2037 | |
| 10 | Dave McKinney# | 1.515 | 2057 | |
| 11 | Tom Thornton | 1.519 | 2043 | |
| 12 | Bryan Miller# | 1.537 | 2060 | |
| 13 | Domingo Galló | 1.561 | 2040 | |
| 14 | Don Alistair# | 1.585 | 2060 | |
| 15 | George Ramos | 1.588 | 2056 | |
| 16 | Orlando Díaz# | 1.631 | 2059 | |
| 17 | Logan Wrighton | 1.676 | 2052 | |
| 18 | Rory May# | 1.700 | 2060 | |
| 19 | Ángel Toledo | 1.701 | 2037 | |
| 20 | Mike Russell# | 1.725 | 2060 | |
| 21 | Yermolay Olhivsky | 1.736 | 2045 | |
| 22 | Bobby Johnson# | 1.747 | 2060 | |
| 23 | Jack Faircloth# | 1.751 | 2059 | |
| 24 | Javier Salinas# | 1.770 | 2059 | |
| 25 | Leonard Sheppard# | 1.774 | 2062 | |
| 26 | Bob Bradley# | 1.789 | 2060 | |
| 27 | Teddy Harvey# | 1.790 | 2054 | |
| 28 | Ronald Hensball | 1.791 | 2053 | |
| 29 | Luis Domínguez# | 1.818 | 2061 | |
| 30 | Tony Smith# | 1.826 | 2060 | |
| 31 | Juan Corona | 1.831 | 2050 | |
| 32 | Michael Adkins# | 1.836 | 2058 | |
| 33 | Juan Cruz# | 1.841 | 2060 | |
| 34 | Wilson Valenzuela | 1.853 | 2033 | |
| 35 | Sidney Jones | 1.862 | 2050 | |
| 35 | Al Casey# | 1.862 | 2060 | |
| 35 | Jorge Ortíz# | 1.862 | 2056 | |
| 38 | Nick Jacobs# | 1.868 | 2062 | |
| 39 | Jeremy Robinson# | 1.916 | 2057 | |
| 40 | Francisco Encarnación# | 1.952 | 2049 | |
| 41 | Pedro Rodríguez | 1.956 | 2040 | |
| 42 | Patrick Meeks# | 1.958 | 2057 | |
| 43 | Millard Whipp | 1.962 | 2039 | |
| 44 | Trent Troubridge# | 1.971 | 2057 | |
| 45 | Derrick Pearson | 1.983 | 2054 | |
| 46 | Silas Brown | 1.985 | 2052 | |
| 47 | Javier Salinas# | 1.993 | 2060 | |
| 48 | Billy Warren# | 2.000 | 2060 | |
| 48 | Zhao-hui Li | 2.000 | 2039 | |
| 50 | Sergio Gómez | 2.004 | 2033 | |
| 51 | José García# | 2.008 | 2059 | |
| 52 | Xing-fu Weng# | 2.019 | 2057 | |
| 53 | Mark Chandler# | 2.027 | 2061 | |
| 54 | Pete Gross# | 2.032 | 2060 | |
| 55 | Anthony Payne | 2.038 | 2053 | |
| 56 | Lou Bancroft# | 2.044 | 2061 | |
| 57 | Jesús Cruz | 2.054 | 2035 | |
| 58 | Jung-keun Kim# | 2.059 | 2061 | |
| 59 | Ramón Santos# | 2.063 | 2060 | |
| 60 | Jesús Costa# | 2.064 | 2056 | |
| 60 | Richard Tanner# | 2.064 | 2052 | |
| 62 | Fernando Feliciano# | 2.065 | 2060 | |
| 62 | César Gutiérrez | 2.065 | 2033 | |
| 64 | António Morterero | 2.077 | 2036 | |
| 64 | Kun-young Cho | 2.077 | 2035 | |
| 66 | Ricardo Hernández | 2.095 | 2044 | |
| 67 | Ed Molloy | 2.097 | 2032 | |
| 68 | Juan Ibarra# | 2.102 | 2059 | |
| 69 | Greg Ayala | 2.103 | 2040 | |
| 69 | Donald Carr | 2.103 | 2056 | |
| 69 | Jorge Veráquez | 2.103 | 2036 | |
| 72 | Jack Hammer# | 2.106 | 2052 | |
| 72 | Ray Spencer | 2.106 | 2052 | |
| 74 | Liu-liang Lei | 2.111 | 2043 | |
| 75 | José García# | 2.112 | 2060 | |
| 76 | Rodger Hunter | 2.114 | 2042 | |
| 77 | Carlos Pereira# | 2.124 | 2059 | |
| 77 | Myung-woo Kang# | 2.124 | 2059 | |
| 79 | Pedro Rodríguez | 2.140 | 2041 | |
| 80 | Kendrick McAllister# | 2.146 | 2059 | |
| 81 | Mario Quintero | 2.157 | 2036 | |
| 82 | Brandon Martin# | 2.167 | 2059 | |
| 83 | Bernard Miller | 2.171 | 2043 | |
| 84 | Edward Small# | 2.184 | 2054 | |
| 85 | Andrei Demian# | 2.195 | 2060 | |
| 86 | William Averett | 2.196 | 2042 | |
| 87 | Etienne de Ruijter# | 2.197 | 2059 | |
| 88 | Kolya Putilov | 2.203 | 2047 | |
| 89 | Juan Rodríguez# | 2.208 | 2052 | |
| 90 | Doug Morgan# | 2.215 | 2056 | |
| 91 | Bob Smithley# | 2.220 | 2056 | |
| 92 | Marty Davis# | 2.221 | 2057 | |
| 93 | Vladsislas Meierhold | 2.225 | 2043 | |
| 93 | Bryan Miller# | 2.225 | 2061 | |
| 95 | Gerardo Tobías | 2.227 | 2046 | |
| 96 | Javier Salinas# | 2.235 | 2058 | |
| 97 | Ray Campbell# | 2.243 | 2059 | |
| 98 | Hyeon-uk Sa | 2.250 | 2036 | |
| 98 | John Deemer | 2.250 | 2042 | |
| 100 | Albert Longoria# | 2.292 | 2060 |
