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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Ramiro Blanco | 0.697 | 2051 | |
| 2 | Rush Moore# | 1.059 | 2060 | |
| 3 | Pedro Soto# | 1.119 | 2052 | |
| 4 | Rafael Flores# | 1.264 | 2059 | |
| 5 | Nicholas Reyes# | 1.362 | 2056 | |
| 6 | Daniel Cummins# | 1.484 | 2059 | |
| 7 | Lee Kennedy# | 1.517 | 2060 | |
| 8 | Pierre-Jean Jung# | 1.642 | 2054 | |
| 9 | Nick Hensley# | 1.651 | 2057 | |
| 10 | Richard Stevenson# | 1.664 | 2057 | |
| 11 | Norm Scott# | 1.665 | 2060 | |
| 12 | Pedro Morales | 1.688 | 2056 | |
| 13 | Derek Carter# | 1.745 | 2053 | |
| 14 | Tom Schaefer# | 1.778 | 2058 | |
| 15 | Ramón Gonzago# | 1.780 | 2056 | |
| 16 | Glenn Hughes# | 1.793 | 2057 | |
| 17 | Salomão Dresel | 1.820 | 2056 | |
| 18 | Jeremiah Harris# | 1.837 | 2052 | |
| 19 | León Berroa# | 1.880 | 2051 | |
| 20 | Alberto Gonzáles# | 1.948 | 2055 | |
| 21 | Shawn Zimmerman# | 2.014 | 2056 | |
| 22 | John Black# | 2.017 | 2057 | |
| 23 | Andrew Wilkes-Krier# | 2.029 | 2055 | |
| 24 | Terry Welch | 2.031 | 2051 | |
| 25 | Manuel Javier# | 2.048 | 2056 | |
| 26 | Alejandro Martínes | 2.051 | 2051 | |
| 27 | Jai Challinor | 2.118 | 2053 | |
| 28 | Dave Sandoval# | 2.132 | 2053 | |
| 29 | Tobias Opsteegh | 2.153 | 2054 | |
| 30 | Jerry Bishop | 2.155 | 2050 | |
| 31 | Fred Boman# | 2.160 | 2057 | |
| 32 | Juan Cruz# | 2.180 | 2059 | |
| 33 | Sinfronio Tiongson | 2.200 | 2052 | |
| 34 | Walt Gregory# | 2.201 | 2051 | |
| 35 | Juan Carlos Robles | 2.236 | 2055 | |
| 35 | Álex Tobías# | 2.236 | 2052 | |
| 37 | Chip Sizemore# | 2.263 | 2050 | |
| 38 | Lou Thompson# | 2.265 | 2052 | |
| 39 | Goris Braams# | 2.323 | 2054 | |
| 40 | Armando Flores | 2.362 | 2051 | |
| 41 | Mark Mitchell# | 2.382 | 2056 | |
| 42 | Quan Situ# | 2.400 | 2052 | |
| 43 | Bennett Dodd# | 2.403 | 2056 | |
| 44 | Carlos Jiménez | 2.404 | 2052 | |
| 45 | Júlio Medina# | 2.455 | 2050 | |
| 46 | Ricardo Ortíz | 2.478 | 2051 | |
| 47 | Ron Woods# | 2.481 | 2057 | |
| 48 | Ricardo Tirado# | 2.487 | 2054 | |
| 49 | Pham Phung# | 2.491 | 2058 | |
| 50 | Jaime Pérez | 2.531 | 2055 | |
| 50 | Jason Minor | 2.531 | 2049 | |
| 52 | Jaime Trujillo# | 2.534 | 2053 | |
| 53 | Juan González# | 2.535 | 2057 | |
| 54 | José Guevara | 2.540 | 2052 | |
| 55 | Christos Tunnicliffe | 2.543 | 2054 | |
| 56 | Dobrica Karkunica | 2.549 | 2053 | |
| 57 | Jorge Flores# | 2.551 | 2057 | |
| 58 | Eugene Blake | 2.560 | 2052 | |
| 59 | Javier Caraballo# | 2.563 | 2053 | |
| 60 | Robert Walls# | 2.571 | 2053 | |
| 61 | Carlos Burgos | 2.580 | 2053 | |
| 62 | Arturo Sánchez | 2.589 | 2055 | |
| 62 | Shawn Zimmerman# | 2.589 | 2057 | |
| 62 | Darius Brooks# | 2.589 | 2055 | |
| 65 | Dennis Abbeel | 2.596 | 2053 | |
| 66 | Li-ping Cheng# | 2.606 | 2054 | |
| 67 | Rubén Quintana# | 2.613 | 2057 | |
| 68 | Domingo Rovlaz | 2.623 | 2051 | |
| 68 | Brian Dalton | 2.623 | 2051 | |
| 70 | José Luna# | 2.632 | 2058 | |
| 71 | Mink Langelaan# | 2.641 | 2060 | |
| 72 | Fergus Littleworth | 2.658 | 2054 | |
| 73 | Lee Pochin | 2.670 | 2052 | |
| 74 | Dermot Bibby# | 2.672 | 2056 | |
| 75 | José Juárez# | 2.683 | 2060 | |
| 76 | Santiago Gonzáles# | 2.700 | 2056 | |
| 77 | Alberto Gonzáles# | 2.712 | 2056 | |
| 78 | Juan Sánchez | 2.718 | 2055 | |
| 79 | Ramón Gonzago# | 2.726 | 2055 | |
| 80 | Lorenzo Silva# | 2.734 | 2051 | |
| 81 | Javier Velázquez# | 2.736 | 2057 | |
| 82 | José Tapia# | 2.760 | 2054 | |
| 83 | Jesús Costa# | 2.774 | 2055 | |
| 84 | Joshua Ames | 2.776 | 2050 | |
| 85 | Wiyoto Djajadiningrat# | 2.782 | 2048 | |
| 86 | David Luna# | 2.786 | 2053 | |
| 87 | Daniel Valdés# | 2.793 | 2056 | |
| 87 | António Martínez# | 2.793 | 2059 | |
| 89 | Mauro Ramos# | 2.799 | 2051 | |
| 90 | Dave Hill# | 2.802 | 2055 | |
| 91 | Xiao-peng Zhu# | 2.805 | 2060 | |
| 92 | Su-min Kim# | 2.827 | 2056 | |
| 93 | Horace Cooper# | 2.836 | 2056 | |
| 94 | Travis Davis# | 2.837 | 2060 | |
| 95 | Juan Carlos Rodríguez | 2.852 | 2054 | |
| 96 | Luis Rea# | 2.856 | 2060 | |
| 96 | León Berroa# | 2.856 | 2050 | |
| 96 | Hou-kang Wu# | 2.856 | 2056 | |
| 96 | Hsin Ning | 2.856 | 2052 | |
| 100 | Hou-kang Wu# | 2.870 | 2055 |
