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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salas, Orlando | RF | Free Agent | 24 | 09/04/2036 | Carolina | PUR | Right | Right | 6' 2" | 200 lbs | - |
| Salazar, Carson | SS | Columbia River Rats | 22 | 09/27/2038 | Waterloo | USA | Right | Right | 6' 1" | 190 lbs | - |
| Sanders, Peter | LF | Monroeville Yinzers | 23 | 11/09/2037 | Burke | USA | Left | Left | 6' 6" | 225 lbs | - |
| Sanders, Sandy | 2B | Free Agent | 23 | 10/08/2037 | Linganore-Bartonsville | USA | Right | Right | 6' 0" | 200 lbs | - |
| Sandoval, José | SP | Pontiac Godfathers | 20 | 08/23/2040 | Fremont | USA | Right | Right | 5' 11" | 170 lbs | - |
| Sankey, Joseph | SP | Holy City Herons | 22 | 07/25/2039 | Nassau | BAH | Right | Right | 6' 1" | 195 lbs | - |
| Santana, Félix | RP | Pontiac Godfathers | 21 | 12/16/2039 | Carúpano | VEN | Right | Right | 6' 2" | 190 lbs | - |
| Santos, Raúl | RP | Pontiac Godfathers | 22 | 09/20/2038 | Utuado | PUR | Right | Right | 6' 3" | 205 lbs | - |
| Sarpaneva, Sampo | SP | Yucca Valley Yellows | 24 | 12/29/2036 | Cegléd | HUN | Right | Right | 6' 1" | 195 lbs | - |
| Sasthi, Ekata | SS | Huntington Hermit Crabs | 20 | 02/07/2041 | Surat | IND | Left | Right | 6' 5" | 175 lbs | - |
| Schlöndorff, Clemens | RP | Pontiac Godfathers | 24 | 04/07/2037 | Chico | USA | Right | Right | 6' 2" | 200 lbs | - |
| Schneider, Jim | RP | Free Agent | 22 | 10/18/2038 | Brick | USA | Right | Right | 6' 0" | 190 lbs | - |
| Schneider, Jon | C | Smoky Mountain Hobeaus | 23 | 11/01/2037 | Brownsville | USA | Switch | Right | 6' 4" | 220 lbs | - |
| Scott, Steve | C | Free Agent | 24 | 07/20/2037 | Hamden | USA | Right | Right | 6' 5" | 215 lbs | - |
| Shalabh, Aukthya | RP | Grand Forks Caterpillars | 22 | 12/15/2038 | Kalyan | IND | Left | Right | 5' 11" | 170 lbs | - |
| Sharp, Noel | SP | Pontiac Godfathers | 21 | 11/25/2039 | Atlanta | USA | Right | Right | 6' 2" | 200 lbs | - |
| Shaw, Jerry | RP | Monroeville Yinzers | 24 | 04/16/2037 | Pacific Grove | USA | Right | Right | 5' 10" | 170 lbs | - |
| Shelton, Aldred | C | Huntington Hermit Crabs | 23 | 08/07/2038 | Harrisville | USA | Right | Right | 6' 4" | 220 lbs | - |
| Shen, Jing-xiang | 2B | Yucca Valley Yellows | 22 | 10/31/2038 | Taichung | TPE | Right | Right | 6' 0" | 180 lbs | - |
| Silva, Fernando | CF | Pontiac Godfathers | 22 | 07/12/2039 | Ponce | PUR | Left | Left | 6' 2" | 195 lbs | - |
| Singer, Rhys | RP | Pontiac Godfathers | 20 | 10/25/2040 | London | ENG | Switch | Right | 6' 2" | 180 lbs | - |
| Skinner, Brad | 2B | Holy City Herons | 23 | 04/28/2038 | Lockport | USA | Right | Right | 6' 0" | 200 lbs | - |
| Smulders, Carsten | CF | Smoky Mountain Hobeaus | 23 | 03/07/2038 | Willemstad | CUR | Right | Right | 6' 3" | 190 lbs | - |
| Sosa, Emílio | SP | Grim Reapers | 22 | 06/27/2039 | San Juan de la Maguana | DOM | Right | Right | 6' 1" | 175 lbs | - |
| Sosa, Lúcio | CF | Smoky Mountain Hobeaus | 20 | 01/20/2041 | La Romana | DOM | Left | Left | 6' 5" | 200 lbs | - |
| Soto, Gabriel | SP | Philadelphia Liberty U-24 | 24 | 12/19/2036 | Palencia | ESP | Right | Right | 6' 2" | 200 lbs | - |
| Stolk, Nicol | CF | Pontiac Godfathers | 24 | 10/16/2036 | Montaña Rey | CUR | Left | Left | 6' 0" | 190 lbs | - |
| Strickland, Curt | 1B | Columbia River Rats | 22 | 07/24/2039 | Muskegon | USA | Right | Right | 6' 3" | 200 lbs | - |
| Suzuki, Hiroya | RP | Monroeville Yinzers | 22 | 04/23/2039 | Fukaya | JPN | Right | Right | 6' 3" | 190 lbs | - |
| Sáenz, Luis | 1B | Smoky Mountain Hobeaus | 22 | 03/31/2039 | Metairie | USA | Right | Right | 6' 8" | 235 lbs | - |
