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| Thursday, November 24th , 2061 |
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| MSL Panama City Piranhas: Fired Manager Cody Blackburn. |
| MSL Panama City Piranhas: Signed Manager Anthony Mitchell. |
| Monday, November 14th , 2061 |
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| MSL Philadelphia Liberty: Signed Manager Armando Ortíz. |
| Wednesday, November 2nd , 2061 |
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| MSL Detroit Elite: Received SP Javier Fernández from the international complex. |
| Thursday, October 27th , 2061 |
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| RF Casper Muijlwijk retired from professional baseball. |
| C Ryo Maruyama retired from professional baseball. |
| 3B Ramón Soto retired from professional baseball. |
| SP Brent Dorst retired from professional baseball. |
| 3B Katsumi Sano retired from professional baseball. |
| SP Juan Rivera retired from professional baseball. |
| 1B Hayden Musgrave retired from professional baseball. |
| C José Cruz retired from professional baseball. |
| RP Jorge Rivera retired from professional baseball. |
| RP Sansan Palhinha retired from professional baseball. |
| CL Tommy Stenis retired from professional baseball. |
| CL Rodrigo Flores retired from professional baseball. |
| 1B Julián Rodríguez retired from professional baseball. |
| 1B Mark Moss retired from professional baseball. |
| 2B Lee Hill retired from professional baseball. |
| 3B Randy Webber retired from professional baseball. |
| RP Octávio Sáenz retired from professional baseball. |
| RP Jin Tsang retired from professional baseball. |
| Pitching Coach Don Robertson retires. |
| Pitching Coach Wu-shiun Lao retires. |
| Manager Cosmo Bjorkenheim retires. |
| MSL Memphis Mockingbirds: Hitting Coach Pat Hopkins leaves the team, his contract was not renewed |
| MSL Philadelphia Liberty: Manager Manuel Rodríguez leaves the team, his contract was not renewed |
| MSL Detroit Elite: Signed Pitching Coach Arturo Santiago to a 2-year contract extension. |
| MSL Echo Park Lakers: Signed Hitting Coach Felipe Bruno to a 2-year contract extension. |
| Monday, September 5th , 2061 |
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| MSL Philadelphia Liberty: Hitting Coach Curt Finley retires. |
