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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Robert Carlson | 2.727 | 2053-2057 | |
| 2 | José Pérez | 3.168 | 2051-2060 | |
| 3 | Edmund Rochefort | 3.377 | 2050-2057 | |
| 4 | Drew Cullen | 3.518 | 2027-2035 | |
| 5 | Mario Ruíz | 3.584 | 2023-2031 | |
| 6 | Roy Alsobrook | 3.700 | 2028-2038 | |
| 7 | Steve Sanford | 3.708 | 2050-2060 | |
| 8 | Andrew Shoemaker | 3.782 | 2049-2057 | |
| 9 | Manny Guerra# | 3.794 | 2052-2063 | |
| 10 | Victor Brey | 3.813 | 2021-2028 | |
| 11 | Mauro Ramos# | 3.917 | 2056-2062 | |
| 12 | Katsumoto Ine | 3.921 | 2047-2051 | |
| 13 | Mario Silva | 3.942 | 2042-2055 | |
| 14 | Patrick Ibáñez | 3.961 | 2035-2046 | |
| 15 | Marvin Stevens | 3.987 | 2043-2056 | |
| 16 | Iwan Vroom | 4.000 | 2052-2062 | |
| 17 | António López | 4.084 | 2041-2050 | |
| 18 | Vic Lee | 4.130 | 2049-2058 | |
| 19 | Gary Barber | 4.155 | 2021-2033 | |
| 20 | Chae-seong Kim | 4.156 | 2023-2033 | |
| 21 | Noboru Kokawa | 4.209 | 2048-2054 | |
| 22 | Claudio Díaz | 4.267 | 2022-2031 | |
| 23 | Ikaia Duncalf | 4.278 | 2045-2054 | |
| 24 | Luis Hernández | 4.374 | 2030-2037 | |
| 25 | Chris Evans | 4.383 | 2050-2057 | |
| 26 | Tim Moore# | 4.398 | 2055-2063 | |
| 27 | Wop Baars | 4.411 | 2032-2041 | |
| 28 | Danny Byrd | 4.413 | 2044-2050 | |
| 29 | Arthur Stevenson | 4.502 | 2046-2054 | |
| 30 | Miguel Aguirre | 4.570 | 2053-2061 | |
| 31 | Pedro Negrón | 4.606 | 2050-2058 | |
| 32 | Matt Davenport | 4.619 | 2029-2037 | |
| 33 | Jorge Cedeño | 4.640 | 2033-2037 | |
| 34 | José Salinas | 4.728 | 2017-2027 | |
| 35 | Gustavo Rivera | 4.729 | 2050-2062 | |
| 36 | King Fletcher | 4.912 | 2023-2030 | |
| 37 | Steve Young | 5.126 | 2042-2049 | |
| 38 | Willie Cameron | 5.351 | 2016-2031 | |
| 39 | Reynaldo Sánchez | 5.785 | 2024-2032 | |
| 40 | Earl Brown | 6.000 | 2023-2031 | |
| 41 | Marcos Mesa | 6.015 | 2023-2030 |
