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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salinas, José | SP | Colorado Billy Goats | 17 | 06/26/2045 | Santo Domingo | DOM | Right | Right | 6' 2" | 175 lbs | - |
| Sanders, Mark | RP | Boston Patriots | 25 | 09/01/2036 | Eastlake | USA | Left | Left | 6' 0" | 195 lbs | $280,000 |
| Sandoval, Martín | RP | Free Agent | 17 | 01/11/2045 | Guadalupe | CRC | Switch | Right | 6' 1" | 170 lbs | - |
| Santingo, Ángel | SP | Free Agent | 36 | 01/15/2026 | Santo Domingo | DOM | Right | Right | 5' 11" | 200 lbs | - |
| Saunders, Joe | LF | Hollywood Shredders | 31 | 07/24/2030 | Sanford | USA | Left | Left | 6' 0" | 200 lbs | $9,000,000 |
| Schneider, John | RP | Northern Virginia Rainbow Mermaids | 22 | 03/06/2040 | Berea | USA | Right | Right | 5' 9" | 165 lbs | $280,000 |
| Scholde, Alois | CF | Boston Patriots | 18 | 06/16/2044 | Vienna | AUT | Right | Right | 6' 0" | 170 lbs | - |
| Seymour, Floyd | RP | Toronto Thunder | 25 | 09/06/2036 | Jackson | USA | Right | Left | 6' 7" | 225 lbs | $280,000 |
| Sheffield, Clint | C | New Orleans Voodoo | 25 | 12/04/2036 | Upland | USA | Right | Right | 6' 0" | 200 lbs | $280,000 |
| Shibata, Yoshifumi | C | Hollywood Shredders | 16 | 07/30/2045 | Kure | JPN | Right | Right | 6' 3" | 190 lbs | - |
| Shirley, Adam | RP | Seattle Rocketeers | 22 | 07/07/2040 | New Berlin | USA | Right | Right | 6' 0" | 175 lbs | $280,000 |
| Siddorn, Charles | RP | Boston Patriots | 23 | 12/07/2038 | Kingston upon Hull | ENG | Right | Right | 6' 2" | 200 lbs | $280,000 |
| Silva, Gilberto | RF | Boston Patriots | 31 | 11/05/2030 | San Alejo | SLV | Right | Right | 6' 2" | 185 lbs | $3,332,800 |
| Silvas, Raúl | LF | Free Agent | 17 | 03/07/2045 | Santo Domingo | DOM | Left | Left | 6' 0" | 175 lbs | - |
| Simon, Bill | CF | Toronto Thunder | 26 | 05/19/2036 | Sunrise Manor | USA | Right | Right | 6' 4" | 205 lbs | $280,000 |
| Simpson, Joe | RP | Boston Patriots | 25 | 03/06/2037 | Sun City Center | USA | Right | Right | 6' 0" | 195 lbs | $280,000 |
| Sims, Mark | RP | Hollywood Shredders | 23 | 02/23/2039 | New York | USA | Right | Right | 6' 2" | 200 lbs | $280,000 |
| Slaymaker, Lance | C | Toronto Thunder | 33 | 03/04/2029 | Akron | USA | Right | Right | 6' 0" | 200 lbs | $8,000,000 |
| Smalls, Elijah | CF | Toledo Stingers | 24 | 05/25/2038 | Brooklyn | USA | Right | Right | 6' 0" | 165 lbs | $280,000 |
| Smith, Ben | C | Colorado Billy Goats | 16 | 08/27/2045 | Kingston | JAM | Left | Right | 6' 1" | 175 lbs | - |
| Somera, Danilo | SS | New Orleans Voodoo | 25 | 05/03/2037 | New Orleans | USA | Right | Right | 6' 0" | 185 lbs | $280,000 |
| Spaceman, Leo | RF | Northern Virginia Rainbow Mermaids | 29 | 03/12/2033 | Phoenix | USA | Switch | Left | 6' 1" | 195 lbs | $8,800,000 |
| Spee, Roel | RF | Free Agent | 22 | 07/10/2040 | Willemstad | CUR | Right | Left | 6' 2" | 200 lbs | - |
| Stansberry, Darryl | CF | Seattle Rocketeers | 30 | 09/17/2031 | San Francisco | USA | Right | Right | 6' 2" | 200 lbs | $4,500,000 |
| Stevens, Keith | C | Colorado Billy Goats | 27 | 08/07/2034 | Whitman | USA | Left | Right | 6' 0" | 200 lbs | $3,100,000 |
| Stewart, Nick | RP | Hollywood Shredders | 32 | 01/29/2030 | Neenah | USA | Left | Left | 5' 11" | 185 lbs | $2,000,000 |
| Strong, Tim | RP | Toledo Stingers | 39 | 02/16/2023 | Quincy | USA | Left | Left | 6' 4" | 205 lbs | - |
| Suarze, Juan | LF | Toronto Thunder | 29 | 06/25/2033 | Los Dos Caminos | VEN | Right | Right | 6' 4" | 200 lbs | $9,000,000 |
| Sun, Kai-ge | SP | Boston Patriots | 16 | 01/04/2046 | Jiaojiang | CHN | Left | Left | 6' 1" | 165 lbs | - |
| Sánchez, Carlos | 2B | Buffalo White Walkers | 26 | 01/05/2036 | Havana | CUB | Right | Right | 6' 0" | 200 lbs | $280,000 |
| Sánchez, Jesús | SP | Free Agent | 32 | 02/25/2030 | West Covina | USA | Right | Right | 6' 2" | 200 lbs | - |
| Sánchez, Víctor | LF | Boston Patriots | 29 | 01/23/2033 | Cotuí | DOM | Left | Right | 6' 4" | 195 lbs | $8,500,000 |
