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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salinas, Javier | SP | Philadelphia Liberty Reserves | 24 | 10/02/2038 | Villa Bruzual | VEN | Right | Right | 6' 0" | 180 lbs | - |
| Salinas, Júlio | 2B | Sacramento Redlegs | 29 | 12/01/2033 | Higüey | DOM | Switch | Right | 6' 4" | 200 lbs | - |
| Sandoval, Dorian | SS | Montreal Machine | 26 | 12/09/2036 | Wichita | USA | Right | Right | 6' 2" | 200 lbs | - |
| Sandoval, Octávio | 3B | Philadelphia Liberty Reserves | 26 | 07/14/2037 | Chiclayo | PER | Right | Right | 6' 2" | 200 lbs | - |
| Santos, Jorge | 1B | Bakersfield Nobles | 27 | 12/19/2035 | Managua | NCA | Right | Right | 6' 3" | 190 lbs | - |
| Santos, Pepe | 1B | Free Agent | 31 | 06/22/2032 | Pedro Brand | DOM | Left | Left | 6' 8" | 200 lbs | - |
| Sasthi, Ekata | SS | Syracuse Squirrel Monkeys | 22 | 02/07/2041 | Surat | IND | Left | Right | 6' 5" | 180 lbs | - |
| Sato, Yoshimasa | SP | Baton Rouge Brass | 30 | 07/16/2033 | Tonosho | JPN | Right | Right | 6' 3" | 210 lbs | $18,000,000 |
| Saucedo, Juan | 1B | Free Agent | 29 | 09/01/2034 | Araure | VEN | Left | Left | 6' 4" | 200 lbs | - |
| Scott, Pete | RP | Syracuse Squirrel Monkeys | 27 | 06/26/2036 | Houston | USA | Right | Right | 6' 2" | 200 lbs | $280,000 |
| Sercombe, Jordan | CF | Sacramento Redlegs | 25 | 01/22/2038 | Belize | BLZ | Right | Right | 6' 2" | 190 lbs | - |
| Seymour, Floyd | RP | Montreal Machine | 26 | 09/06/2036 | Jackson | USA | Right | Left | 6' 7" | 225 lbs | $280,000 |
| Silver, Duke | SP | Free Agent | 31 | 07/20/2032 | San Francisco | USA | Left | Right | 5' 10" | 190 lbs | - |
| Sizemore, Chip | SP | Free Agent | 32 | 07/11/2031 | Tacoma | USA | Right | Right | 6' 2" | 200 lbs | - |
| Small, Eric | 1B | Baton Rouge Brass | 22 | 10/21/2040 | Butte | USA | Right | Right | 6' 0" | 190 lbs | $280,000 |
| Smith, Derek | SS | Free Agent | 31 | 12/20/2031 | Miami | USA | Right | Right | 6' 0" | 190 lbs | - |
| Smith, John | LF | Baton Rouge Brass | 24 | 01/18/2039 | Stanton | USA | Right | Right | 6' 2" | 200 lbs | - |
| Smith, Peter | RP | Philadelphia Liberty Reserves | 24 | 03/31/2039 | Hoffman Estates | USA | Left | Left | 6' 2" | 200 lbs | $280,000 |
| Somera, Danilo | SS | Baton Rouge Brass | 26 | 05/03/2037 | New Orleans | USA | Right | Right | 6' 0" | 185 lbs | $280,000 |
| Soto, Gabriel | SP | Philadelphia Liberty Reserves | 26 | 12/19/2036 | Palencia | ESP | Right | Right | 6' 2" | 205 lbs | - |
| Soto, Ángelo | 1B | Philadelphia Liberty Reserves | 30 | 03/07/2033 | Turmero | VEN | Right | Right | 6' 0" | 200 lbs | $280,000 |
| Spaceman, Leo | RF | Free Agent | 30 | 03/12/2033 | Phoenix | USA | Switch | Left | 6' 1" | 195 lbs | - |
| Spencer, William | RP | Philadelphia Liberty Reserves | 33 | 11/10/2029 | Boston | USA | Switch | Right | 6' 1" | 200 lbs | - |
| Spillman, Bill | 2B | Free Agent | 34 | 07/01/2029 | Chicago | USA | Switch | Right | 6' 0" | 200 lbs | - |
| Stansberry, Darryl | CF | Free Agent | 31 | 09/17/2031 | San Francisco | USA | Right | Right | 6' 2" | 205 lbs | - |
| Steele, Ed | SS | Baton Rouge Brass | 22 | 03/10/2041 | Elk River | USA | Right | Right | 6' 4" | 190 lbs | - |
| Stewart, Nick | SP | Sacramento Redlegs | 33 | 01/29/2030 | Neenah | USA | Left | Left | 5' 11" | 190 lbs | $2,000,000 |
| Stone, Cliff | C | Bakersfield Nobles | 31 | 04/09/2032 | Slidell | USA | Right | Right | 6' 4" | 200 lbs | - |
| Strong, Tim | RP | Ellenburg Fighting Dachshunds | 40 | 02/16/2023 | Quincy | USA | Left | Left | 6' 4" | 205 lbs | - |
| Stroud, Rod | LF | Pennsauken Flyers | 24 | 04/30/2039 | Atchison | USA | Left | Right | 6' 1" | 195 lbs | - |
| Sullivan, Eric | C | Jersey City Tritons | 29 | 10/20/2033 | Sun City West | USA | Right | Right | 6' 4" | 205 lbs | - |
| Sullivan, Ron | C | Free Agent | 31 | 02/21/2032 | Denver | USA | Left | Right | 5' 11" | 200 lbs | - |
| Suzuki, Hiroya | RP | Monongahela Monsters | 24 | 04/23/2039 | Fukaya | JPN | Right | Right | 6' 3" | 195 lbs | - |
| Sánchez, José | 2B | Free Agent | 32 | 10/18/2030 | Lagunillas | VEN | Right | Right | 6' 3" | 200 lbs | - |
| Sánchez, Sancho | RP | Ellenburg Fighting Dachshunds | 25 | 03/02/2038 | Rowland Heights | USA | Left | Left | 6' 7" | 225 lbs | - |
