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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saldana, Romel | RP | Amarillo Warheads | 21 | 01/03/2041 | Isabela | PHI | Right | Right | 6' 4" | 195 lbs | - |
| Salter, Carl | SP | Philadelphia Liberty U-21 | 21 | 07/16/2040 | Lake Forest | USA | Right | Right | 6' 4" | 210 lbs | - |
| Samorukov, Aleksandr | CF | Bethlehem Angel Kitties | 19 | 11/25/2042 | Vilnius | LTU | Right | Right | 6' 2" | 195 lbs | - |
| Sandoval, Juan | RP | Memphis Music | 21 | 07/23/2040 | San Bernardino | MEX | Right | Right | 6' 5" | 195 lbs | - |
| Santiago, José | C | Bompton Baby Lakers | 21 | 06/17/2040 | Guadalupe | PAN | Right | Right | 6' 0" | 205 lbs | - |
| Santos, Pancho | C | Memphis Music | 21 | 04/22/2041 | Los Chiles | CRC | Right | Right | 6' 3" | 200 lbs | - |
| Sawyer, Dan | SP | Free Agent | 19 | 03/29/2043 | Bronx | USA | Left | Right | 5' 9" | 160 lbs | - |
| Scott, Monty | 2B | Amarillo Warheads | 19 | 02/17/2043 | Lynwood | USA | Right | Right | 6' 5" | 195 lbs | - |
| Scutt, Jacob | SS | Ogallala Octopi | 19 | 03/24/2043 | Nassau | BAH | Right | Right | 6' 4" | 190 lbs | - |
| Sekine, Toshiharu | 3B | Free Agent | 19 | 10/29/2042 | Toyonaka | JPN | Right | Right | 6' 2" | 180 lbs | - |
| Sheppard, Kai | 1B | Philadelphia Liberty U-21 | 19 | 12/01/2042 | Sunderland | ENG | Right | Right | 6' 1" | 195 lbs | - |
| Sheppard, Leonard | SP | Bompton Baby Lakers | 21 | 11/25/2040 | Sheboygan | USA | Switch | Right | 6' 4" | 200 lbs | - |
| Sherman, Mike | SP | Memphis Music | 19 | 09/17/2042 | Jasmine Estates | USA | Right | Left | 6' 2" | 185 lbs | - |
| Shimada, Shinji | RP | Free Agent | 19 | 02/23/2043 | Kure | JPN | Right | Left | 6' 4" | 190 lbs | - |
| Sierra, Miguel | 1B | Ogallala Octopi | 19 | 08/27/2042 | Maturín | VEN | Right | Right | 6' 3" | 200 lbs | - |
| Sims, Alex | RP | Shady Side Zoomies | 20 | 03/06/2042 | Kenai | USA | Switch | Right | 6' 1" | 185 lbs | - |
| Smith, Bob | RP | Amarillo Warheads | 20 | 03/16/2042 | Lakeland | USA | Left | Left | 6' 1" | 175 lbs | - |
| Solano, Guarçia | 1B | Watford City Trash Pandas | 20 | 10/14/2041 | Valencia | VEN | Right | Right | 6' 2" | 200 lbs | - |
| Soto, Jesús | SP | Memphis Music | 20 | 02/23/2042 | Newport News | USA | Left | Left | 6' 7" | 200 lbs | - |
| Spears, Dan | RP | Ogallala Octopi | 20 | 02/11/2042 | Oklahoma City | USA | Left | Left | 6' 1" | 180 lbs | - |
| Sreekanthan, Arup | SP | Free Agent | 20 | 04/14/2042 | Madurai | IND | Right | Left | 6' 0" | 175 lbs | - |
| Stadler, Alois | SP | Bompton Baby Lakers | 20 | 08/17/2041 | Litomerice | CZE | Left | Left | 6' 2" | 180 lbs | - |
| Stanbra, Aaron | LF | Memphis Music | 21 | 02/22/2041 | Middelburg | RSA | Right | Right | 6' 2" | 170 lbs | - |
| Stephenson, Roland | CF | Tijuana Toros | 21 | 12/30/2040 | Brooklyn | USA | Left | Left | 6' 0" | 180 lbs | - |
| Stone, Greg | SP | Ogallala Octopi | 20 | 05/12/2042 | Laredo | USA | Right | Right | 6' 8" | 205 lbs | - |
| Sugimoto, Ogai | SP | Shady Side Zoomies | 21 | 05/02/2041 | Kanazawa | JPN | Left | Right | 6' 4" | 195 lbs | - |
| Sun, Fa-tang | C | Ogallala Octopi | 21 | 11/29/2040 | Taipei | TPE | Left | Right | 6' 7" | 210 lbs | - |
| Suzuki, Tadayoshi | C | Bethlehem Angel Kitties | 20 | 10/06/2041 | Inazawa | JPN | Right | Right | 6' 7" | 215 lbs | - |
| Szema, Hsin-ta | RF | Tijuana Toros | 19 | 03/10/2043 | Kaohsiung | TPE | Left | Left | 6' 0" | 175 lbs | - |
| Sánchez, Francisco | SP | Watford City Trash Pandas | 20 | 10/29/2041 | Barranquilla | COL | Right | Right | 6' 2" | 185 lbs | - |
