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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salinas, Guillermo | SS | MSL Vancouver Grey Wolves | 18 | 02/11/2037 | Puerto Plata | DOM | Right | Right | 6' 2" | 180 lbs | - |
| Sameno, Jorge | 1B | MSL St. Louis Coeur | 17 | 05/23/2038 | Manzanillo | CUB | Right | Right | 6' 2" | 180 lbs | - |
| Sandoval, Octávio | 3B | MSL Athletic Club KC U-18 | 17 | 07/14/2037 | Chiclayo | PER | Right | Right | 6' 2" | 190 lbs | - |
| Santana, Gustavo | C | MSL Athletic Club KC U-18 | 17 | 09/05/2037 | Puerto Plata | DOM | Right | Right | 6' 1" | 180 lbs | - |
| Sasaki, Hideaki | SP | MSL Athletic Club KC U-18 | 17 | 06/01/2038 | Asahikawa | JPN | Right | Right | 6' 4" | 185 lbs | - |
| Serrano, Roberto | RP | Free Agent | 18 | 09/24/2036 | Soyapango | SLV | Left | Left | 6' 4" | 195 lbs | - |
| Serrano, Rodrigo | RP | MSL St. Louis Coeur | 18 | 05/03/2037 | Las Teyerías | VEN | Right | Right | 6' 7" | 200 lbs | - |
| Shalabh, Aukthya | RP | MSL Montana Pandas | 16 | 12/15/2038 | Kalyan | IND | Left | Right | 5' 10" | 165 lbs | - |
| Shen, Jing-xiang | 2B | MSL Montana Pandas | 16 | 10/31/2038 | Taichung | TPE | Right | Right | 6' 0" | 165 lbs | - |
| Silva, José | SP | MSL Vancouver Grey Wolves | 17 | 12/14/2037 | Lima | PER | Switch | Right | 5' 11" | 165 lbs | - |
| Silva, Raúl | C | MSL Seattle Rocketeers | 17 | 06/27/2038 | Loreto | MEX | Right | Right | 6' 1" | 175 lbs | - |
| Sin, Chin-seok | C | MSL New Orleans Voodoo | 18 | 03/01/2037 | Seoul | KOR | Right | Right | 6' 0" | 190 lbs | - |
| Siu, Jing-sheng | 3B | MSL Buffalo White Walkers | 17 | 08/02/2037 | Shanghai | CHN | Right | Right | 6' 2" | 185 lbs | - |
| Smerdon, Paul | RP | MSL St. Louis Coeur | 17 | 08/26/2037 | Willemstad | CUR | Right | Right | 6' 1" | 175 lbs | - |
| Solís, Luis | CF | MSL New Orleans Voodoo | 17 | 08/28/2037 | Almansa | ESP | Left | Left | 6' 2" | 180 lbs | - |
| Sosa, Gustavo | SP | MSL Buffalo White Walkers | 17 | 07/24/2037 | Santiago | DOM | Right | Right | 6' 3" | 185 lbs | - |
| Sosa, Jorge | RP | MSL Boston Patriots | 18 | 04/22/2037 | Chimaltenango | GUA | Right | Right | 5' 10" | 155 lbs | - |
| Soto, Gabriel | SP | MSL Athletic Club KC U-18 | 18 | 12/19/2036 | Palencia | ESP | Right | Right | 6' 2" | 185 lbs | - |
| Steffansson, Yngve | SP | MSL Ft. Worth Cattlemen | 17 | 03/01/2038 | Karvia | FIN | Right | Right | 6' 3" | 180 lbs | - |
| Stevens, Bob | SP | MSL New Orleans Voodoo | 18 | 08/28/2036 | Queens | USA | Left | Right | 6' 0" | 180 lbs | - |
| Stewart, Scott | SP | MSL New Orleans Voodoo | 18 | 03/16/2037 | Plainfield | USA | Left | Left | 6' 4" | 185 lbs | - |
| Stinnett, John | RP | Free Agent | 24 | 02/22/2031 | Asheboro | USA | Right | Left | 6' 0" | 175 lbs | - |
| Suzuki, Naoaki | 2B | MSL Boston Patriots | 18 | 09/12/2036 | Otawara | JPN | Left | Right | 6' 3" | 175 lbs | - |
| Suárez, Manuel | SP | MSL St. Louis Coeur | 17 | 10/01/2037 | Yaritagua | VEN | Right | Right | 6' 0" | 175 lbs | - |
