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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sa, Ze-dong | RF | MSL Montana Pandas | 18 | 09/26/2043 | Taipei | TPE | Left | Left | 6' 2" | 195 lbs | - |
| Saldaña, António | SP | MSL Colorado Billy Goats | 17 | 12/26/2043 | Sanchez | CRC | Right | Right | 6' 2" | 175 lbs | - |
| Salinas, Robinson | 2B | MSL Las Vegas Flamingos | 17 | 02/01/2044 | Santiago | DOM | Left | Right | 6' 4" | 185 lbs | - |
| Sandoval, Javier | 1B | Free Agent | 20 | 11/25/2040 | Santo Domingo | DOM | Left | Right | 6' 2" | 200 lbs | - |
| Sano, Katsumi | 3B | Free Agent | 20 | 11/15/2040 | Kitakyushu | JPN | Right | Right | 6' 3" | 200 lbs | - |
| Santos, Augusto | RP | Free Agent | 18 | 04/07/2043 | Huitan | GUA | Right | Right | 6' 3" | 185 lbs | - |
| Scott, Norm | SP | Free Agent | 20 | 08/09/2041 | Abbotsford | USA | Left | Right | 6' 2" | 185 lbs | - |
| Sheppard, Kai | 1B | MSL Philadelphia Liberty | 18 | 12/01/2042 | Sunderland | ENG | Right | Right | 6' 1" | 195 lbs | - |
| Sherman, Rory | SP | MSL Memphis Mockingbirds | 19 | 09/23/2042 | Centereach | USA | Right | Right | 5' 11" | 170 lbs | - |
| Sinke, Dieter | 3B | MSL Pittsburgh Kingfishers | 17 | 07/23/2044 | Princess Quarter | SIM | Right | Right | 6' 1" | 180 lbs | - |
| Slimak, Pavol | SP | MSL Panama City Piranhas | 17 | 09/06/2044 | Bardejov | SVK | Left | Left | 6' 7" | 200 lbs | - |
| Smit, Maurice | SS | MSL Colorado Billy Goats | 19 | 06/05/2042 | Hilversum | NED | Switch | Right | 6' 5" | 200 lbs | - |
| Soto, Armando | DH | MSL Panama City Piranhas | 17 | 12/05/2043 | Gómez Palacio | MEX | Right | Right | 5' 10" | 165 lbs | - |
| Soto, Ramón | LF | Free Agent | 20 | 12/06/2040 | Estelí | NCA | Left | Left | 6' 4" | 200 lbs | - |
| Stenis, Tommy | RP | Free Agent | 20 | 09/29/2041 | Cul De Sac | SIM | Right | Right | 6' 5" | 195 lbs | - |
| Sugimoto, Shunsen | SP | MSL Panama City Piranhas | 18 | 11/18/2042 | Chikugo | JPN | Left | Left | 6' 5" | 190 lbs | - |
| Suzuki, Nobukazu | C | Free Agent | 18 | 09/09/2043 | Yasato | JPN | Right | Right | 5' 9" | 175 lbs | - |
| Sáenz, Octávio | SP | Free Agent | 19 | 02/23/2042 | Jaibón | DOM | Right | Right | 6' 0" | 170 lbs | - |
| Sánchez, Germán | DH | MSL Panama City Piranhas | 18 | 09/17/2043 | Petare | VEN | Right | Right | 6' 2" | 195 lbs | - |
| Sánchez, José | CF | MSL Ft. Worth Cattlemen | 17 | 04/28/2044 | Santo Domingo | DOM | Left | Left | 6' 3" | 180 lbs | - |
| Sánchez, José | 3B | MSL Memphis Mockingbirds | 19 | 08/06/2042 | Fresno | USA | Right | Right | 6' 2" | 185 lbs | - |
| Sánchez, Juan | SP | MSL Panama City Piranhas | 17 | 04/04/2044 | Guatire | VEN | Left | Left | 6' 2" | 175 lbs | - |
| Sánchez, Júlio | CF | MSL Pittsburgh Kingfishers | 17 | 04/03/2044 | Moa | CUB | Right | Right | 6' 2" | 185 lbs | - |
