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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saikawa, Matsusuke | 1B | Syracuse Squirrel Monkeys | 34 | 06/26/2025 | Chofu | JPN | Left | Left | 6' 4" | 200 lbs | $800,000 |
| Salas, Jorge | SP | Free Agent | 29 | 03/23/2030 | Santo Domingo | DOM | Left | Left | 6' 1" | 200 lbs | - |
| Sale, Tom | C | Free Agent | 27 | 12/26/2031 | Gautier | USA | Left | Right | 6' 0" | 200 lbs | - |
| Sandoval, Luis | 3B | Ft. Myers Marlins | 27 | 09/12/2031 | Guantanamo | CUB | Right | Right | 6' 3" | 200 lbs | $280,000 |
| Sanford, Steve | SP | Salt Lake City Buzz | 35 | 10/22/2023 | Berwick | USA | Right | Right | 6' 2" | 205 lbs | $1,011,000 |
| Santos, Jorge | RP | Free Agent | 32 | 06/23/2027 | San Miguel | CRC | Left | Left | 6' 3" | 200 lbs | - |
| Saracho, Jaicus | RF | Free Agent | 35 | 02/28/2024 | Malasila | PHI | Right | Right | 6' 2" | 205 lbs | - |
| Schmidt, Pat | 1B | Ft. Myers Marlins | 29 | 02/13/2030 | Medford | USA | Right | Right | 6' 2" | 205 lbs | - |
| Schoutens, Take | LF | Free Agent | 26 | 06/04/2033 | Willemstad | CUR | Left | Right | 6' 1" | 200 lbs | - |
| Scott, Jerry | SP | Ft. Myers Marlins | 25 | 06/21/2034 | Bonifay | USA | Right | Right | 6' 0" | 185 lbs | - |
| Shimizu, Sumitomo | 2B | Salt Lake City Buzz | 32 | 01/09/2027 | Kitakyushu | JPN | Right | Right | 5' 9" | 195 lbs | $660,000 |
| Shini, Yaichiro | RP | Montreal Machine | 34 | 09/27/2024 | Kashihara | JPN | Right | Right | 6' 6" | 195 lbs | $5,700,000 |
| Silva, Carl | 1B | Free Agent | 25 | 03/23/2034 | Nashville | USA | Switch | Left | 6' 2" | 205 lbs | - |
| Silver, Albert | RP | Montreal Machine | 31 | 07/15/2028 | Austin | USA | Left | Right | 6' 2" | 195 lbs | - |
| Sim, Pyeong-ho | 2B | Free Agent | 33 | 03/25/2026 | Seongnam | KOR | Switch | Right | 6' 4" | 195 lbs | - |
| Simpson, Pat | RF | Free Agent | 25 | 03/25/2034 | Southold | USA | Right | Right | 6' 1" | 200 lbs | - |
| Slaughter, Lonnie | RP | Hialeah Dodos | 30 | 12/23/2028 | Kirkland | USA | Right | Right | 6' 4" | 205 lbs | - |
| Sloan, Ray | LF | Hamilton Thunderbirds | 32 | 04/16/2027 | New York | USA | Left | Left | 6' 0" | 200 lbs | $280,000 |
| Smith, Kevin | SS | Austin Black Mambas | 25 | 10/25/2033 | Corinth | USA | Right | Right | 6' 0" | 195 lbs | - |
| Soto, Eduardo | RP | Pawnee ParksNRec | 29 | 02/10/2030 | Ecatepec | MEX | Left | Left | 6' 2" | 200 lbs | - |
| Stafford, Craig | C | Free Agent | 27 | 05/06/2032 | Ashland | USA | Switch | Right | 6' 4" | 200 lbs | - |
| Stokes, Curt | SP | Austin Black Mambas | 33 | 05/04/2026 | Middleton | USA | Left | Left | 6' 1" | 190 lbs | $280,000 |
| Sundquist, Derek | C | Salt Lake City Buzz | 27 | 09/27/2031 | Milton-Freewater | USA | Right | Right | 5' 10" | 200 lbs | - |
| Swan, Ishaan | 1B | Sunset District Fog | 33 | 01/07/2026 | St. George | BER | Left | Right | 6' 0" | 190 lbs | $13,000,000 |
| Sáenz, Orlando | RF | Free Agent | 34 | 03/07/2025 | Santiago | DOM | Switch | Right | 5' 10" | 200 lbs | - |
| Sánchez, Alfredo | C | Free Agent | 25 | 07/24/2034 | Bajos de Haina | DOM | Right | Right | 6' 0" | 200 lbs | - |
| Sánchez, Francisco | SP | Vermont Lake Monsters | 24 | 08/28/2035 | Caledonia | USA | Right | Right | 6' 4" | 205 lbs | - |
| Sánchez, Francisco | LF | Vermont Lake Monsters | 26 | 08/23/2033 | Havana | CUB | Left | Left | 6' 0" | 190 lbs | - |
| Sánchez, José | 2B | Montreal Machine | 28 | 10/18/2030 | Lagunillas | VEN | Right | Right | 6' 3" | 200 lbs | - |
| Sánchez, Juan | SP | Ft. Myers Marlins | 25 | 07/24/2034 | Carolina | PUR | Right | Right | 5' 10" | 175 lbs | - |
| Sánchez, Rubén | RP | Austin Black Mambas | 35 | 10/31/2023 | Santiago | CHI | Right | Right | 6' 3" | 200 lbs | - |
